PO0019 Increased Throughput of INtip A?inity Purification for Larger Sample Volume
來源:IMCS
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作者:P. Nikki Sitasuwan1*, Huey J. Nguyen1, Todd Mullis2, Chris Kemp3, Casey Snodgrass4, L. Andrew Lee1*
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發布時間: 960天前
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929 次瀏覽
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Dispersive pipette extraction is a patented INtip? micro-extraction platform that leverages turbulent mixing of the resinwithin the pipette tip to increase interaction time between resin and sample. Coupling this core technology to the highlyflexible, automated liquid handling system – Hamilton? Microlab STAR? workstation – enables rapid INtip purification ofantibodies, recombinant proteins and various other recombinant proteins in a consistent manner. Here, we address one ofthe major challenges in high throughput monoclonal antibody purification, which has been processing sample volumes over3 mL using INtip micro-purification technologies. The workflow is outlined inFigure 1.
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